The HBZ gene, a key player in HTLV-1 pathogenesis
Abstract Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL) and is also associated with a variety of lymphocyte-mediated diseases.The HTLV-1 basic leucine zipper (HBZ) gene, found to PS1 be consistently expressed in ATL, has recently been the subject of intensive research efforts.In this review, we summarize rec